The HTEC-510 is user friendly, provides worry free maintenance, can be easily switched between methods, and most importantly has superb sensitivity.

Ultra-High Sensitivity Electrochemical Detection

The best advantage of using electrochemical (EC) detection is the sensitivity. Eicom will never compromise when improving the electrochemical detector’s sensitivity. The combination of the HTEC-510, HPLC-Electrochemical Detector and the appropriate applications will easily ensure 160 amol sensitivity for dopamine and serotonin, and 5 fmol for acetylcholine.

Turn-Key System

The HTEC-510 is the optimized HPLC-ECD (Electrochemical Detection) system. Analytical applications of electrochemical detection have already been prepared, all you need to do is choose the appropriate method and follow the detailed protocol. Then you can easily get the results.

Easy to Maintain

The simple compact design of the HTEC-510 (HPLC-ECD) allows for easy maintenance. If you have any questions, we will be happy to help you every step of the way.

Superior Customer Support

We assign a trained application specialist to work directly with you from the beginning.  This way we build an efficient working relationship and can help resolve any issues immediately.

The HTEC-510 replaces the HTEC-500

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Eicom’s Innovative Cell Design

  • Ultrasensitive, 30 fg of dopamine
  • Graphite electrode often ready to use < 30 mins after start-up
  • No tools to access the working electrode
  • Easy to clean or change the working electrode


The key to the sensitivity is the cell design. Eicom relies on a spring loaded mechanism that always maintains the proper pressure. This structure allows the detector to quickly stabilize after the cell is opened and closed. Another benefit is that the working electrode can easily be accessed without any tools. In this way, the electrode can easily be wiped clean and reinstalled to insure maximum sensitivity.

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System The degasser, pump and ECD are mounted in a temperature controlled cabinet. A manual injector is also included.
System Control Integrated central control
Materials in Contact With Solvents PEEK and FEP, metal free materials
Flow Line Pressure Resistance 20 MPa
(1st Channel)
Amperometric DC mode
(2nd Channel) Option
Coulometric ECD or UV/Vis detection
Dimensions 250 (w) x 399 (h) x 365 (d) mm/approx 10″ x 16″ x 14.5″
Weight 18 kg with amperometric detector cell/40 lb

Electrochemical Detection (1st channel)

Electrochemical Detection
(1st channel)
Expandable for second channel with model EPC-510
Principle Amperometric DC mode
Applied Potential Range 0 to +/- 2000 mV, 1 mV steps
Integrator Output Range Auto-zero point +/- 5 V, 0.1 nA/1 mV
Auto-Zero Working Range +/- 500 nA
Detector Cell Easy open/close with constant pressure system
Working Electrode Exchangeable disk
Standard Working Electrode Graphite, S/N 250% improved from glassy carbon
Working Electrode Options Platinum, modified gold, pure graphite, glassy carbon, silver
Surface Volume of Working Electrode Changeable, 25 or 50 µm thickness with 3.5 or 7 mm width
Reference Electrode Material Ag/AgCl, solid phase
Counter Electrode Material Stainless steel 316
Time Constant Filter 1.0/1.5/3 min
Noise Level Less than 3 pA with dummy flow of R-W 1 MΩ R-C 2 MΩ at 0 mV

High Performance Pump

High Performance Pump
Single Stroke Replacement Volume 4 µl, Φ2 x1.3 mm stroke
Principle Isocratic, reciprocal dual piston pump
Pulsation Control Controllable on/off capability. Computer programmed auto-quenching pulse system by variable stroke speed drive during each stroke.
Pistons Material Sapphire glass
Check Valves Φ1/16″ two check valves at the outlet and a single valve at the inlet
Piton Seal High density polyethylene, Teflon® also available
Flow Rate Range 0 to 750 µl/min
Pulse Damper Not required
Error Monitor Over pressure limit error, check valve error, motor error


Temperature Control Range 20-45°C at 25°C ambient
Control Procedure Peltier element to both cool and heat

Solvent Degassing Unit

Solvent Degassing Unit
Principle Online
Channel Two
Internal Volume Ch 1 300 µl/Ch 2 7.5 ml


Communication All connectors are easy to access outside the component
ECD Integrator Out Analog, 0.1 nA = 1 mV, 10 V full range
Pump Pressure Monitor Out Analog, 10 MPa = 100 mV
Temperature Monitor Out Analog 10°C = 100 mV.
Pump Error Out 1.0 sec contact closure signal out. Works to stop autosampler.
Stop/Run Outer Trigger In Stop/run ECD and pump unit. 0.5 sec contact closure signal in. Works for auto stop and auto start. Main power required to be on to receive the signal.
Auto-Zero Trigger In Runs auto-zero, 0.5 sec contact closure signal in
Manual Injector Switching Signal In After receiving the signal, the delay out sends signal out.
Inject Signal In After receiving the signal, the delay out sends signal out. Works to communicate with an autosampler.
Delay Out 2 ports. 0 and 3 sec delay with 1.0 sec contact closure signal.

The specifications are subject to change without notice.